San Francisco 49ers

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McCaffrey exits 49ers’ game in Buffalo with knee injury

McCaffrey slid down untouched in the backfield after taking a toss, then immediately went to the 49ers' medical tent and eventually the locker room.

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Live 49ers updates: Niners face Bills in snowy Buffalo

Follow the action in Buffalo, with kickoff at 5:20 p.m.

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49ers pregame: Brock Purdy returns, Josh Dobbs will back up rather than Brandon Allen

While the 49ers welcome Brock Purdy back to the starting lineup at snow-covered Highmark Stadium, his immediate backup will be Josh Dobbs rather than Brandon Allen.

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49ers practice report: What’s latest with Brock Purdy before Bills game?

The 49ers listed Brock Purdy as a limited participant while Nick Bosa and Trent Williams were among those not practicing Thursday before Sunday night's game at Buffalo.

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49ers mailbag: Dissecting defensive doom, Shanahan’s fate

An extensive mailbag ushers the 49ers (5-5) into their Week 12 preparations for Sunday's visit to the Green Bay Packers (7-3).

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49ers expect Kittle back at practice, will evaluate Bosa throughout the week

The 49ers assessed their wounded Monday and went over what went wrong in fourth quarter of loss to Seattle.

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49ers report card: Playoff hopes dim as team looks mentally, physically ragged

Falling apart in the fourth quarter is the legacy the 49ers (5-5) are solidifying under coach Kyle Shanahan, be it in the playoffs or now against regular-season NFC West foes.

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49ers-Seahawks pregame: Kittle scratched; Williams, Bosa active

Tight end George Kittle will miss his second game this season with a hamstring injury, although the 49ers will have Trent Williams and Nick Bosa today against the visiting Seattle Seahawks.

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49ers’ Nick Bosa could use a break — and may not get one unless he breaks down physically

As much as the 49ers would like to reduce Nick Bosa's workload, they're less of a team when he's on the sideline resting.

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McCaffrey assesses his 49ers season debut and all the ‘Instagram doctors’ who chimed in

McCaffrey divulged more about his return from Achilles tendinitis in both legs that kept him out for the first half of the season.

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49ers’ Shanahan puts Deebo-Moody-Pepper squabble to rest

49ers coach Kyle Shanahan met with the parties involved after a sideline incident involving receiver Deebo Samuel, long-snapper Taybor Pepper and place kicker Jake Moody.

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Inman: 10 things to catch my eye in 49ers’ escape from Tampa

Brock Purdy's connection with George Kittle, plus Nick Bosa's hip injury, shouldn't be overlooked from the 49ers' chaotic comeback in Tampa Bay.

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49ers kicker Moody: Deebo owes no apology for sideline dispute

Deebo Samuel confronted Jake Moody during the 49ers' game against the Bucs after he missed three field goals.

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Kurtenbach: If the 49ers are Super Bowl worthy, they have a funny way of showing it

The Niners can't seem to get out of their own way, even on their best days.

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What the 49ers said after wild win over Buccaneers

Kyle Shanahan warned his team that today's game would be gritty. He was right.

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49ers Studs and Duds: Jake Moody, the Niners narrowly escape Tampa Bay

Jake Moody missed three field goals, but made a game-winner as time expired.

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49ers’ Christian McCaffrey talks about his injury and recovery

McCaffrey:` I wouldn't be out here if it was still bothering me. I feel great.'

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49ers’ first post-bye challenge is defending Bucs QB Baker Mayfield

With Charvarius Ward on bereavement leave, the 49ers carry on and will face Tampa Bay and Baker Mayfield Sunday.